Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Neuroanatomic/neuropathologic correlates in schizophrenia.

A J Waldman1

  • 1Department of Psychiatry, College of Medicine, University of Florida, Gainesville.

Southern Medical Journal
|September 1, 1992
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Fluoxetine in dementia of the Alzheimer's type: prominent adverse effects and failure to improve cognition.

The Journal of clinical psychiatry·1994
Same author

Pseudocyesis in a schizophrenic woman of child-bearing age.

Psychosomatics·1992
Same author

Sometimes when you hear hoofbeats ... two cases of inherited metabolic diseases with initial presentation of psychiatric symptoms.

The Journal of neuropsychiatry and clinical neurosciences·1992
Same author

Chlorpromazine & appetite.

Journal of the American Geriatrics Society·1991
Same author

A Creutzfeldt-Jakob-like syndrome due to polypharmacy.

Southern medical journal·1990

Schizophrenia involves brain changes, including enlarged ventricles. This may stem from birth trauma and genetic factors, potentially affecting brain development.

Area of Science:

  • Neuroscience
  • Psychiatry
  • Genetics

Background:

  • Schizophrenia is associated with neuropathologic changes.
  • Increased ventricle-brain ratios are a documented finding in schizophrenia patients.

Purpose of the Study:

  • To explore potential causes of increased ventricle-brain ratios in schizophrenia.
  • To investigate the role of birth trauma and genetic predisposition in schizophrenia development.

Main Methods:

  • Review of neuropathologic studies from the 1980s.
  • Analysis of reported ventricle-brain ratios in schizophrenic individuals.

Main Results:

  • Neuropathologic changes are evident in schizophrenia.
  • Elevated ventricle-brain ratios are frequently observed.

Related Experiment Videos

Conclusions:

  • Birth trauma and genetic factors may contribute to enlarged ventricles and schizophrenia.
  • Embryogenic anomalies in the hippocampus and other brain regions are implicated in the illness.