Related Experiment Videos
Glucagon-like peptide 1 (GLP-1) and eating
Jean-Pierre Gutzwiller1, Lukas Degen, Ludwig Heuss
1Division of Gastroenterology, University Hospital, Basel, Switzerland.
Abstract:
New information regarding gastrointestinal mechanisms that participate in the control of food intake has extended our understanding of appetite control. Although each new signaling pathway discovered in the gut is a potential target for drug development in the treatment of obesity, the growing number of such signaling molecules indicates that a highly complex process controls food intake. The present summary focuses on the role of glucagon-like peptide 1 (GLP-1) in this regulatory process. The different biological effects of GLP-1 (glucose-lowering properties, inhibition of appetite and food intake) provide a powerful impetus for development of GLP-1-based new drugs.