Related Experiment Video
Updated: Aug 23, 2026

Control of Eating Behavior Using a Novel Feedback System
Published on: May 8, 2018
Lessons in the interactions of hormones and ingestive behavior
1Department of Psychiatry, Medical Center, University of Cincinnati, 2170 East Galbraith Road, Box 670559, Cincinnati, OH 45237, USA. steve.woods@psychiatry.uc.edu
Abstract:
Research by Jim Gibbs and Gerry Smith from the Bourne Laboratory in the early 1970s demonstrated that peptide signals from the digestive system, especially cholecystokinin (CCK), have a profound effect on ingestive behavior. My laboratory consequently pursued a parallel course with the hormone insulin. Integrating the research on meal-generated signals, such as CCK, with adiposity-indicating signals, such as insulin, has progressed a long way, thanks in large part to suggestions and inputs from Gerry Smith along the way. This short article documents that progress.
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