Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Considerations for setting up a small-animal imaging facility.

Brenda A Klaunberg1, Martin J Lizak

  • 1National Institutes of Health Mouse Imaging Facility, 10 Center Drive, Room B1D-69, Bethesda, MD 20892, USA.

Lab Animal
|July 6, 2004
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Ibrutinib disrupts blood-tumor barrier integrity and prolongs survival in rodent glioma model.

Acta neuropathologica communications·2024
Same author

A PARP inhibitor, rucaparib, improves cardiac dysfunction in <i>ADP-ribose-acceptor hydrolase 3</i> ( <i>Arh3</i> ) deficiency.

bioRxiv : the preprint server for biology·2023
Same author

Mono-ADP-ribosyltransferase 1 ( <i>Artc1</i> )-deficiency decreases tumorigenesis, increases inflammation, decreases cardiac contractility, and reduces survival.

bioRxiv : the preprint server for biology·2023
Same author

<i>ADP-ribose-acceptor hydrolase 2</i> ( <i>Arh2</i> ) deficiency results in cardiac dysfunction, tumorigenesis, inflammation, and decreased survival.

bioRxiv : the preprint server for biology·2023
Same author

Amphotericin B Penetrates into the Central Nervous System Through Focal Disruption of the Blood Brain Barrier in Experimental Hematogenous <i>Candida</i> Meningoencephalitis.

Antimicrobial agents and chemotherapy·2019
Same author

EGFR-targeted therapy results in dramatic early lung tumor regression accompanied by imaging response and immune infiltration in EGFR mutant transgenic mouse models.

Oncotarget·2016

Establishing a successful mouse imaging facility requires careful planning and staffing. This guide details the process for creating such a specialized research resource.

Area of Science:

  • Biomedical research
  • Small-animal imaging
  • Laboratory animal science

Background:

  • Noninvasive, in vivo longitudinal studies in small animals are crucial for research.
  • Advanced imaging equipment and trained personnel are necessary for these studies.
  • High costs and complexity can be barriers to establishing imaging facilities.

Purpose of the Study:

  • To describe the planning and staffing of the National Institutes of Health (NIH) Mouse Imaging Facility.
  • To highlight key considerations for designing and implementing similar small-animal imaging facilities.
  • To provide a practical framework for resource allocation and personnel management in imaging research.

Main Methods:

  • Detailed planning of facility infrastructure and equipment acquisition.

Related Experiment Videos

  • Strategic staffing to ensure availability of trained personnel.
  • Development of operational protocols and user support systems.

    • Main Results:

    • Successful establishment of a functional NIH Mouse Imaging Facility.
    • Identification of critical factors for efficient facility operation and user satisfaction.
    • Demonstration of a viable model for supporting small-animal imaging research.

    Conclusions:

    • Careful planning and dedicated staffing are essential for creating effective small-animal imaging facilities.
    • Addressing equipment, personnel, and operational challenges is key to facility success.
    • The described approach provides a valuable blueprint for other institutions seeking to develop similar resources.