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The effect of ureteric stents on urine flow: reflux

L J Cummings1, S L Waters, J A D Wattis

  • 1School of Mathematical Sciences, University of Nottingham, NG7 2RD Nottingham, UK. Linda.Cummings@nottingham.ac.uk

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Renal Drug Excretion: Effect of Urine pH, Flow Rate, and Drug pKa

The pH of urine, the drug's pKa, and the urine flow rate are vital parameters for drug reabsorption and excretion. Urinary pH varies between 4.6 and 8.0 and is influenced by diet, drug intake, and the patient's pathophysiology. It affects a drug's ionization state and reabsorption. For instance, carbohydrate-rich food produces alkaline urine promoting drug excretion, while proteins and certain medications like ascorbic acid lead to acidic urine enhancing reabsorption.
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Ureters

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