Related Experiment Video
Updated: Aug 23, 2026

Treatment of Facial Deformities using 3D Planning and Printing of Patient-Specific Implants
Published on: May 23, 2020
[Juvenile gigantomastia. Case report and literature survey]
B Gerber1, A Krause, E-M Lochmüller
1I. Frauenklinik-Innenstadt der Ludwig-Maximilians-Universität München. bernd.gerber@fk-i.med.uni-muenchen.de
Abstract:
A juvenile gigantomastia with wet tender ulceration in a 13-year-old premenarchal girl (155 cm, 51 kg) developed in only 6 months. Treatment consisted of a bilateral reduction mammoplasty with free transplantation of the areolae and nipples and the removal of 4.2 kg of breast tissue. Macroscopically the resections consisted of "white and solid" tissue. Histologically a fibrous-cystic mastopathia was confirmed. It is thus suggested that the etiology of this disease might be related to a local hypersensitivity to estrogen. Mediactions (Tamoxifen) are mostly ineffective. The treatment consisted of reduction plasty.