Biowaiver monographs for immediate release solid oral dosage forms based on biopharmaceutics classification system

H Vogelpoel1, J Welink, G L Amidon

  • 1RIVM-National Institute for Public Health and the Environment, Center for Quality of Chemical-Pharmaceutical Products, P.O. Box 1, 3720 BA Bilthoven, The Netherlands.

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Antiarrhythmic Drugs: Class I Agents as Sodium Channel Blockers

Class I antiarrhythmic drugs are used to treat various types of arrhythmias or irregular heart rhythms. These drugs block the sodium (Na+) channels in the cardiac cells, thereby affecting the movement of electrical impulses across the heart. Class I antiarrhythmic drugs are divided into three subgroups: Class IA, Class IB, and Class IC, each with distinct mechanisms of action and effects on the heart.
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Antiarrhythmic Drugs: Class II Agents as β-Adrenergic Blockers

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Antiarrhythmic Drugs: Class IV Agents as Calcium Channel Blockers

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Bioequivalence studies: Biowaivers

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