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The Use of Reverse Phase Protein Arrays (RPPA) to Explore Protein Expression Variation within Individual Renal Cell Cancers
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Detection of renal cell carcinoma-associated markers via proteome- and other 'ome'-based analyses

Barbara Seliger1, Rudolf Lichtenfels, Roland Kellner

  • 1Third Department of Internal Medicine at the Johannes Gutenberg University, Mainz, Germany. 3-med.klinik.uni-mainz.de

Briefings in Functional Genomics & Proteomics
|July 9, 2004
PubMed

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Proteomics01:33

Proteomics

A proteome is the entire set of proteins that a cell type produces. We can study proteomes using the knowledge of genomes because genes code for mRNAs, and the mRNAs encode proteins. Although mRNA analysis is a step in the right direction, not all mRNAs are translated into proteins.
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term proteomics...