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Related Concept Videos

Tertiary Healthcare System01:21

Tertiary Healthcare System

Specialized care provided over an extended period is called tertiary care. Usually, a primary or secondary care physician will refer a patient to tertiary care. A patient's maximum physical and mental function is restored in tertiary care, which is caused due to the impact of a chronic illness or condition. Tertiary care aims to achieve the highest level of functioning possible while managing chronic illness. For example, a patient who falls and fractures their hip will need secondary care to...
Drug Dosing: Infants and Children01:29

Drug Dosing: Infants and Children

Pediatric patient dosages diverge from adults due to disparities in body surface area, total body water, and extracellular fluid per kilogram of body weight. The dosing regimen considers the variations in pharmacokinetics and pharmacology across distinct age groups, encompassing preterm newborns, infants, young children, older children, and adolescents. Calculation of pediatric patient doses is predicated on determining body surface area, which exhibits a superior correlation with the child's...
Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption01:23

Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption

Understanding the physiological differences in the pediatric population is crucial for effective pharmacotherapy. Neonates, infants, and children exhibit significant variations in gastric pH, gastric emptying time, intestinal transit time, and biliary function. These variations profoundly affect oral drug absorption, necessitating a nuanced approach to pediatric dosing.Neonates present with a unique physiological profile, having a gastric pH greater than 4 and faster and more irregular gastric...
Pharmacokinetics in Pediatric Patients: Drug Distribution01:17

Pharmacokinetics in Pediatric Patients: Drug Distribution

Drug distribution in the pediatric population exhibits unique challenges and considerations due to the physiological differences between children, particularly neonates and infants, and adults. A crucial aspect of pediatric pharmacology is understanding how these differences impact the pharmacokinetics of various drugs, necessitating age-specific dosing strategies to ensure efficacy and safety.Neonates and infants have a higher total body water content, ~75%–90% of their body weight, compared...
Pharmacokinetics in Pediatric Patients: Drug Metabolism01:24

Pharmacokinetics in Pediatric Patients: Drug Metabolism

In pediatric care, understanding the nuances of hepatic drug metabolism is crucial, as it significantly differs from that of adults. This divergence is primarily due to the developmental stage of drug-metabolizing enzymes, which affects how medications are processed in the body. In neonates, for instance, the activity of Phase I enzymes—critical for the initial breakdown of drugs—is markedly reduced, functioning at just 20–40% of the levels seen in adults. This reduction poses a challenge in...
Pharmacokinetics in Pediatric Patients: Drug Excretion01:26

Pharmacokinetics in Pediatric Patients: Drug Excretion

In pediatric medicine, understanding the renal function and drug elimination nuances is crucial for administering safe and effective treatments. Newborns, in particular, display markedly slower renal functions than adults, profoundly affecting how drugs are cleared from their bodies. This slower drug clearance requires clinicians to extend the dosing intervals for many medications to prevent drug accumulation and toxicity while ensuring therapeutic efficacy.One key area where these adjustments...

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Related Experiment Video

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Guidelines for Elective Pediatric Fiberoptic Intubation
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Justification for a pediatric satellite pharmacy at a tertiary-care institution.

V A Hawkins1, M F Powell

  • 1Pediatric Service, MetroHealth Medical Center, Cleveland, OH 44109-1998.

American Journal of Hospital Pharmacy
|September 1, 1992
PubMed
Summary

A new pediatric satellite pharmacy can improve medication safety and care quality for children in hospitals. This specialized pharmacy is projected to enhance pediatric drug use support and yield significant financial benefits over five years.

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Area of Science:

  • Pediatric Pharmacy Practice
  • Health Services Management
  • Medication Safety

Background:

  • Tertiary care medical centers often face challenges in providing specialized pharmaceutical services to pediatric populations.
  • Existing central pharmacy models may not adequately support the unique needs of pediatric patients, leading to medication errors and infection control issues.
  • A significant portion of hospital beds (150 of 742) are dedicated to pediatric care, highlighting the need for improved pharmaceutical support.

Purpose of the Study:

  • To justify the establishment of a dedicated pediatric satellite pharmacy within a tertiary care medical center.
  • To outline the service objectives and anticipated benefits of implementing a pediatric satellite pharmacy.
  • To assess the financial viability and projected return on investment for a pediatric satellite pharmacy.

Main Methods:

  • Proposal development for a pediatric satellite pharmacy, including service objectives and benefit identification.
  • Financial analysis to project the economic impact of the satellite pharmacy over a five-year period.
  • Justification based on identified deficiencies in current pediatric pharmaceutical support and potential for improvement.

Main Results:

  • The proposed pediatric satellite pharmacy is expected to correct medication-related problems and enhance the quality of pediatric care.
  • A financial analysis indicated a projected net gain of approximately $285,000 over five years attributable to the satellite pharmacy.
  • The proposal was approved by hospital administration, with ongoing monitoring by the quality assurance committee.

Conclusions:

  • Implementation of a pediatric satellite pharmacy is a viable strategy to improve medication safety and patient care in pediatric settings.
  • The establishment of a pediatric satellite pharmacy offers significant financial benefits alongside improvements in clinical outcomes.
  • Continuous quality assurance monitoring will be essential to evaluate and ensure the sustained positive impact of the pediatric satellite pharmacy.