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Updated: Aug 14, 2026

A Protocol for Computer-Based Protein Structure and Function Prediction
16:41

A Protocol for Computer-Based Protein Structure and Function Prediction

Published on: November 3, 2011

Sequence-based prediction of protein domains

Jinfeng Liu1, Burkhard Rost

  • 1CUBIC, Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY 10032, USA. liu@cubic.bioc.columbia.edu

Nucleic Acids Research
|July 9, 2004
PubMed
Summary

CHOPnet, a novel de novo method, accurately predicts protein structural domains using neural networks without relying on homology. This computational tool aids structural genomics by improving domain boundary predictions.

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