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A unique circulating inhibitor with specificity for coagulation factor X
1Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205-2101.
An 84-year-old woman presented with extensive cutaneous and gastrointestinal bleeding. Initial laboratory studies revealed a prolonged prothrombin time and activated partial thromboplastin time. Further investigations revealed a circulating anticoagulant with specificity for factor X. The patient's hemorrhage resolved with supportive measures only. Approximately 11 months after presentation, the inhibitor disappeared.
An 84-year-old woman presented with extensive cutaneous and gastrointestinal bleeding. Initial laboratory studies revealed a prolonged prothrombin time and activated partial thromboplastin time. Further investigations revealed a circulating anticoagulant with specificity for factor X. The patient's hemorrhage resolved with supportive measures only. Approximately 11 months after presentation, the inhibitor disappeared.