Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Defense Against Bacterial Pathogens01:31

Defense Against Bacterial Pathogens

3.0K
The human immune system is a complex network of cells, tissues, and organs that work together to defend the body against bacterial infections. It consists of various immune cells, each playing a specific role in the defense mechanism.
Phagocytes
Phagocytes are the frontline soldiers of the immune system. They include neutrophils and macrophages. Neutrophils are the most abundant type of white blood cell and are quickly mobilized to the site of infection. Macrophages are larger cells that patrol...
3.0K
Biological Methods for Microbial Control01:28

Biological Methods for Microbial Control

1.4K
Biological agents offer an effective means of controlling microbial growth by leveraging natural processes like predation, competition, and the secretion of antimicrobial substances.Predatory bacteria such as Bdellovibrio species target and kill pathogens like Salmonella and E. coli. They are widely used in poultry farms to control infections. Myxococcus species help combat plant-pathogenic fungi. These naturally occurring predators serve as eco-friendly alternatives to chemical pesticides and...
1.4K
Gene Regulation in Microbial Communities: Quorum Sensing01:28

Gene Regulation in Microbial Communities: Quorum Sensing

954
Quorum sensing is a mechanism of bacterial communication that enables coordinated gene expression in response to changes in population density. This facilitates collective behaviors that enhance survival, resource acquisition, and ecological adaptation. This process relies on small signaling molecules called autoinducers that accumulate as bacterial populations grow. When a critical threshold concentration of autoinducers is reached, bacterial cells collectively modify gene expression,...
954
Microbial Interactions: Predation01:28

Microbial Interactions: Predation

65
Microbial predation refers to the process by which one microorganism kills and consumes another to obtain nutrients and energy. It encompasses both bacterial and protozoan predators. This interaction plays a crucial role in shaping microbial communities and regulating nutrient cycling.Bacterial Predators: Epibiotic vs. EndobioticBacterial predators are classified based on their mode of attack as either epibiotic or endobiotic. Epibiotic predators, such as Vampirococcus, attach to the surface of...
65
Microbial Interactions: Parasitism01:22

Microbial Interactions: Parasitism

108
Parasitism is a form of microbial interaction in which parasitic microbes exploit a host organism for nutrients and shelter, often at the host's expense. Unlike mutualistic relationships, where both organisms benefit, parasitism benefits only the parasite and harms the host.Classification of ParasitesMicrobial parasites are broadly classified based on their location relative to the host.Ectoparasites remain on the host’s surface, such as the skin or outer tissues, drawing nutrients...
108
Colonisation of Pathogens01:25

Colonisation of Pathogens

77
Pathogen colonization of host tissues is a critical step in the development of infectious diseases. Various pathogenic microorganisms, including bacteria, fungi, viruses, and protozoa, have evolved complex strategies to attach to, invade, and persist within host environments. These mechanisms enable pathogens to establish infections, evade immune responses, and resist antimicrobial treatments.Attachment to Host CellsIn bacteria, colonization typically begins with adherence to host epithelial...
77

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Characterization of <i>Pseudomonas aeruginosa</i> and <i>Acinetobacter calcoaceticus-baumannii</i> complex traumatic wound isolates.

Microbiology spectrum·2026
Same author

Correlation versus causation: <i>Helicobacter pylori</i> population heterogeneity complicates the identification of mutant strain phenotypes.

mSphere·2025
Same author

Cross-laboratory replication of pseudomyxoma peritonei tumor microbiome reveals reproducible microbial signatures.

mSphere·2025
Same author

A unique <i>Helicobacter pylori</i> strain to study gastric cancer development.

Microbiology spectrum·2024
Same author

Dynamics of the Oral Microbiome During Initial Military Training at Fort Benning, Georgia.

Military medicine·2024
Same author

bioRxiv : the preprint server for biology·2023

Related Experiment Video

Updated: May 5, 2026

Studying Microbial Communities In Vivo: A Model of Host-mediated Interaction Between Candida Albicans and Pseudomonas Aeruginosa in the Airways
06:43

Studying Microbial Communities In Vivo: A Model of Host-mediated Interaction Between Candida Albicans and Pseudomonas Aeruginosa in the Airways

Published on: January 13, 2016

8.5K

Frontal and stealth attack strategies in microbial pathogenesis.

D Scott Merrell1, Stanley Falkow

  • 1Uniformed Services University of the Health Sciences, Department of Microbiology and Immunology, 4301 Jones Bridge Road, Bethesda, Maryland 20814, USA. dmerrell@usuhs.mil

Nature
|July 9, 2004
PubMed
Summary

Microbial interactions with human hosts vary widely. Understanding these host-pathogen dynamics is crucial for combating infectious diseases, which remain a leading cause of global mortality.

More Related Videos

Porphyromonas gingivalis as a Model Organism for Assessing Interaction of Anaerobic Bacteria with Host Cells
12:16

Porphyromonas gingivalis as a Model Organism for Assessing Interaction of Anaerobic Bacteria with Host Cells

Published on: December 17, 2015

25.6K
Morphological and Compositional Analysis of Neutrophil Extracellular Traps Induced by Microbial and Chemical Stimuli
14:05

Morphological and Compositional Analysis of Neutrophil Extracellular Traps Induced by Microbial and Chemical Stimuli

Published on: November 4, 2022

2.9K

Related Experiment Videos

Last Updated: May 5, 2026

Studying Microbial Communities In Vivo: A Model of Host-mediated Interaction Between Candida Albicans and Pseudomonas Aeruginosa in the Airways
06:43

Studying Microbial Communities In Vivo: A Model of Host-mediated Interaction Between Candida Albicans and Pseudomonas Aeruginosa in the Airways

Published on: January 13, 2016

8.5K
Porphyromonas gingivalis as a Model Organism for Assessing Interaction of Anaerobic Bacteria with Host Cells
12:16

Porphyromonas gingivalis as a Model Organism for Assessing Interaction of Anaerobic Bacteria with Host Cells

Published on: December 17, 2015

25.6K
Morphological and Compositional Analysis of Neutrophil Extracellular Traps Induced by Microbial and Chemical Stimuli
14:05

Morphological and Compositional Analysis of Neutrophil Extracellular Traps Induced by Microbial and Chemical Stimuli

Published on: November 4, 2022

2.9K

Area of Science:

  • Microbiology
  • Immunology
  • Pathogenesis

Background:

  • Host-microbe interactions encompass a spectrum from symbiosis to lethal competition.
  • Infectious diseases represent a significant global health burden, causing more deaths annually than any other cause.
  • Despite progress, a comprehensive understanding of microbial pathogenesis is still lacking.

Purpose of the Study:

  • To underscore the importance of investigating microbial mechanisms of disease.
  • To highlight the critical need for novel model systems in host-pathogen research.
  • To advance the understanding of host-pathogen interactions.

Main Methods:

  • This study is a review and conceptual analysis.
  • It synthesizes current knowledge on host-pathogen interactions.
  • It emphasizes the need for new experimental models.

Main Results:

  • Host-microbe interactions are complex and can be detrimental.
  • Infectious diseases continue to be a major cause of death worldwide.
  • Existing knowledge gaps necessitate innovative research approaches.

Conclusions:

  • Further research into microbial disease mechanisms is essential.
  • Development of advanced model systems is critical for progress in host-pathogen studies.
  • Continued investigation is vital for addressing the global impact of infectious diseases.