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Isolated ambulatory hypertension is common in outpatients referred to a hypertension centre

A Ungar1, G Pepe, M Monami

  • 1Department of Critical Care Medicine and Surgery, Unit of Gerontology and Geriatrics - Hypertension Centre, University of Florence, and Azienda Ospedaliera Careggi, Florence, Italy. aungar@unifi.it

Journal of Human Hypertension
|July 9, 2004
PubMed

Insights

Isolated ambulatory hypertension, defined as high blood pressure (BP) during monitoring but normal BP in the office, affects over 10% of patients. This condition shows a BP profile similar to sustained hypertension, suggesting broader use of ambulatory BP monitoring.

Area of Science:

  • Cardiology
  • Hypertension Research
  • Clinical Diagnostics

Background:

  • Arterial hypertension diagnosis relies on office blood pressure (OBP) measurements.
  • Ambulatory blood pressure monitoring (ABPM) provides a more comprehensive BP profile.
  • Isolated ambulatory hypertension (IAH) is characterized by elevated ABPM with normal OBP.

Purpose of the Study:

  • To determine the prevalence of IAH in outpatients referred for hypertension evaluation.
  • To analyze the blood pressure profile of patients with IAH.
  • To assess the clinical implications of IAH.

Main Methods:

  • A cohort of 1488 outpatients underwent both OBP measurement and 24-hour ABPM.
  • Patients were classified into subgroups based on OBP and daytime ABPM values.
  • Statistical analysis compared BP profiles between different patient groups.

Main Results:

  • The prevalence of IAH exceeded 10% in the study population.
  • 45.3% of patients with normal OBP exhibited elevated BP during ABPM.
  • IAH patients showed significantly higher night-time BP, 24-h pulse pressure, and BP variability compared to normotensive or white-coat hypertensive individuals.

Conclusions:

  • IAH is a common condition in outpatients evaluated for hypertension.
  • The BP profile in IAH resembles that of sustained hypertension.
  • Expanded indications for ABPM in hypertensive centers are suggested for better patient management.

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