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Iodine-125 brachytherapy of brain stem tumors
Jenö Julow1, Arpád Viola, Tibor Major
1Department of Neurosurgery, St. John's Hospital, Budapest, Hungary. h12494jul@ella.hu
Purpose:
To report on iodine-125 ((125)I) interstitial irradiation in the treatment of brain stem tumors.
Patients And Methods:
Two patients with brain stem tumors were treated with CT- and image fusion-guided (125)I stereotactic brachytherapy.
Results:
By March 2003, the patients had been followed up for 47 and 13 months, respectively. In case 1, the tumor volume was 1.98 cm(3) on the control CT, indicating a 65.5% shrinkage as compared to a target volume of 5.73 cm3 at the time of brachytherapy. In case 2, shrinkage was more distinct. After irradiation, the cyst volume was 0.16 cm(3) on the control MRI, indicating a 97.4% shrinkage as compared to a target volume of 6.05 cm(3) at the time of brachytherapy, i. e., the metastasis had virtually disappeared.
Conclusion:
CT- and image fusion-guided (125)I stereotactic brachytherapy can be performed during the biopsy session. The procedure can be well planned dosimetrically and is surgically precise.
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