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Genetic pathways and new progression markers for prostate cancer defined by microsatellite allelotyping
Rolf von Knobloch1, Lutz Konrad, Peter J Barth
1Department of Urology, Philipps-University Marburg Medical School, Marburg/Lahn, Germany. Rolf.von-Knobloch@med.uni-marburg.de
Der Urologe. Ausg. A
|July 9, 2004
Abstract:
A prospective study was carried out on a large cohort of males undergoing radical retropubic prostatectomy in order to identify genetic marker regions significantly associated with tumor formation. By comprehensive allotyping of chromosomes known to be associated with prostate carcinogenesis, an algorithm could be formulated for the genetic pathway and a method of discrimination between aggressive and less aggressive forms could be identified.