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Cardiovascular care in end-stage renal disease
Insights
Cardiovascular disease (CVD) is a major cause of death in end-stage renal disease (ESRD). Both chronic kidney disease (CKD) and ESRD independently increase CVD risk and complicate treatments, highlighting the need for improved patient care.
Area of Science:
- Nephrology and Cardiology
- Renal Disease Research
- Cardiovascular Health
Background:
- Cardiovascular disease (CVD) is the leading cause of death in end-stage renal disease (ESRD).
- Chronic kidney disease (CKD) and ESRD are recognized as independent risk factors for CVD.
- CKD/ESRD significantly complicates cardiovascular procedures and increases mortality.
Discussion:
- The spectrum of CVD in ESRD encompasses accelerated atherosclerosis, myocardial disease, heart failure, arrhythmias, and valvular heart disease.
- ESRD poses unique challenges in managing cardiovascular risk.
- Interdisciplinary approaches are crucial for addressing CVD in renal disease patients.
Key Insights:
- ESRD independently elevates the risk of developing and worsening cardiovascular conditions.
- The presence of CKD/ESRD necessitates tailored cardiovascular management strategies.
- Early identification and intervention are critical for improving outcomes in ESRD patients with CVD.
Outlook:
- Future research should focus on optimizing cardiovascular care across the ESRD patient journey.
- Exploring novel therapeutic targets for CVD in CKD/ESRD is essential.
- Improving patient outcomes requires integrated care models spanning outpatient, dialysis, transplant, and post-revascularization settings.
Abstract:
Cardiovascular disease (CVD) accounts for the majority of morbidity and mortality in patients with end-stage renal disease (ESRD). Chronic kidney disease, and ESRD as its most severe form, are now acknowledged to be independent risk factors for CVD. The spectrum of CVD includes accelerated atherosclerosis, myocardial disease and heart failure, cardiac arrhythmias, and valvular heart disease. In addition, CKD and ESRD are independent and powerful factors that complicate cardiovascular procedures and have been directly linked to increased mortality. This issue of Advances in Chronic Kidney Disease will explore the spectrum of risk and the opportunities to improve care in ESRD in outpatient management, during dialysis, after kidney transplantation, and in coronary revascularization.
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