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Assessment of Vascular Function in Patients With Chronic Kidney Disease
08:50

Assessment of Vascular Function in Patients With Chronic Kidney Disease

Published on: June 16, 2014

The evaluation of underlying cardiovascular disease among patients with end-stage renal disease

S Susan Hedayati1, Lynda Anne Szczech

  • 1Duke University Medical Center, Department of Medicine, Division of Nephrology, Durham, NC 27710, USA.

Advances in Chronic Kidney Disease
|July 9, 2004
PubMed

Insights

Coronary artery disease (CAD) is common in chronic kidney disease (CKD) patients, yet treatments are underused. This review details diagnostic tests for CAD in end-stage renal disease (ESRD) to guide nephrologists.

Area of Science:

  • Nephrology
  • Cardiology
  • Diagnostic Imaging

Background:

  • Coronary artery disease (CAD) is highly prevalent in patients with chronic kidney disease (CKD).
  • Cardiovascular disease (CVD) mortality interventions are underutilized in this high-risk population.
  • The burden of CVD necessitates better understanding of CAD detection in end-stage renal disease (ESRD).

Purpose of the Study:

  • To review diagnostic tests for CAD detection and evaluation in ESRD patients.
  • To correlate test results with patient outcomes.
  • To provide recommendations for noninvasive CAD evaluation for practicing nephrologists.

Main Methods:

  • Review of studies on exercise electrocardiography testing.
  • Review of studies on pharmacologic stress imaging.
  • Review of studies on single-photon emission computed tomographic myocardial perfusion imaging, electron beam computed tomography, and dobutamine stress echocardiography.

Main Results:

  • Specific diagnostic tests for CAD in ESRD patients were examined.
  • The correlation between these tests and patient outcomes was analyzed.
  • Recommendations for noninvasive CAD evaluation were formulated based on study findings.

Conclusions:

  • Knowledge of specific diagnostic tests is imperative for nephrologists managing ESRD patients with high CAD prevalence.
  • Noninvasive evaluation strategies are crucial for improving outcomes in this population.
  • Further research and guideline adherence can optimize CAD management in CKD patients.

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