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Updated: Aug 23, 2026

Terminal H-reflex Measurements in Mice
Published on: June 16, 2022
Between-days reliability of H-reflexes in human flexor carpi radialis
Shapour Jaberzadeh1, Sheila Scutter, Andrea Warden-Flood
1Department of Physiology, Medical School, Adelaide University, Adelaide, SA 5005, Australia. shapour.jaberzadeh@adelaide.edu.au
Objectives:
To assess between-day reliability of the latency and peak-to-peak amplitude of a technique to elicit the H-reflex and M response of the flexor carpi radialis (FCR) and the ratio of maximum H-reflex and M-response amplitude (Hmax/Mmax).
Design:
Test-retest reliability study.
Setting:
Electrophysiology laboratory at a university.
Participants:
Fifteen consecutively recruited healthy volunteers (8 men, 7 women; age range, 22-65y).
Intervention:
Volunteers were tested on 2 separate days at the same time of day for H-reflex and M response by stimulating the median nerve in the cubital fossa in the presence of a standardized voluntary contraction of the FCR muscle.
Main Outcome Measures:
Onset latencies, peak-to-peak amplitudes, and Hmax/Mmax.
Results:
Latency measurements of H-reflex and M response showed excellent reliability between days, as did the maximum amplitude of the M response. The maximum amplitudes of the H-reflex and Hmax/Mmax ratio were less reliable but still within acceptable limits.
Conclusions:
The H-reflex and M response can be reliably elicited in the FCR. This technique provides a useful clinical tool for diagnostic purposes during the course of neurologic disorders and in preclinical and postclinical intervention studies.
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