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Updated: Aug 23, 2026
Mouse Models Of Helicobacter Infection And Gastric Pathologies
Published on: October 18, 2018
Evaluation of a monoclonal antibody-based test for detection of Helicobacter pylori-specific antigen in stool samples
Julia Crone1, Erin Symonds, Fiona Campbell
1Gastroenterology Unit, Women's and Children's Hospital, North Adelaide, 5006 South Australia, Australia.
Abstract:
A test using monoclonal antibodies for detection of antigen in stool samples was compared with culture and histology for noninfected (n = 25), Helicobacter pylori-infected (n = 25), and Helicobacter felis-infected (n = 6) mice. Sensitivity and specificity were 96%. The monoclonal antibody-based test is therefore a noninvasive technique that is able to diagnose H. pylori infection in mice.
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