Related Experiment Videos
Uterine leiomyoma and menstrual cycle characteristics in a population-based cohort study
J L Marino1, B Eskenazi, M Warner
1School of Public Health, University of California, Berkeley, California 94720-7360, USA.
Background:
We examined the association of uterine leiomyoma with menstrual cycle characteristics in a population of non-care-seeking women.
Methods:
This cross-sectional study uses data from the Seveso Women's Health Study (SWHS), a population-based cohort in Italy. Participants included 341 premenopausal women, 30-60 years old, who had an intact uterus and were not pregnant, lactating, or using oral contraception or intra-uterine devices. We examined the presence of any ultrasound-detected uterine leiomyoma in relation to self-reported menstrual cycle length, flow length and heaviness of flow. The association of leiomyoma number, volume, tissue layer location and axial position with menstrual cycle characteristics was also examined.
Results:
Uterine leiomyomata were detected in 73 women (21.4%). After adjustment for covariates, the presence of a leiomyoma was not significantly related to menstrual cycle length, flow length or heaviness of flow [odds ratio (OR) for scanty flow =1.9, 95% confidence interval (CI) 0.8-4.3; OR for heavy flow =1.3, 95% CI 0.7-2.5; relative to moderate flow]. Number, volume, tissue layer location (subserosal or intramural) and axial position (anterior or posterior) of the leiomyoma were also not related to menstrual cycle characteristics.
Conclusion:
In this Italian population of women not seeking gynaecological care, menstrual characteristics are not related to leiomyoma.
