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Propranolol inhibits IK(Ado) by competitive A1-receptor interaction

B Brandts1, D Dirkmann, R Borchard

  • 1Medizinische Klinik II, Schwerpunkte Kardiologie und Angiologie, Ruhr-Universität Bochum, Hölkeskampring 40, 44625 Herne, Germany. bodo.brandts@rub.de

Zeitschrift Fur Kardiologie
|July 10, 2004
PubMed
Summary

Propranolol inhibits adenosine-induced potassium current (IK(Ado)) in heart cells, independent of beta-receptor blockade. This action may contribute to its anti-arrhythmic effects during myocardial ischemia.

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