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Evaluation of a high-dose dexamethasone-eluting stent
Rainer Hoffmann1, Roswitha Langenberg, Peter Radke
1Medical Clinic I, University Hospital Aachen, Germany. RHoffman@UKAACHEN.de
The American Journal of Cardiology
|July 13, 2004
Abstract:
This study evaluated the safety and efficacy of a dexamethasone-eluting stent with a special high dexamethasone-loading dose for treatment of de novo coronary lesions in 30 patients. Eight patients had in-stent restenosis (restenosis rate 31%) at 6-month follow-up, and the in-stent late lumen loss was 0.96 +/- 0.63 mm due to an average intimal hyperplasia area obstruction of 32 +/- 21%, indicating that high-dose dexamethasone-loaded stents do not significantly reduce neointimal proliferation.