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Related Experiment Videos

Pulp reactions to resin cements.

C H Pameijer1, H R Stanley

  • 1University of Connecticut, School of Dental Medicine.

American Journal of Dentistry
|April 1, 1992
PubMed
Summary

Resin-filled cements show minimal pulp reactions in primates, comparing favorably to controls like zinc oxide-eugenol. These dental materials are expected to be well-tolerated by human pulp when properly applied.

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Area of Science:

  • Dental Materials Science
  • Biocompatibility Studies
  • Restorative Dentistry

Background:

  • Resin-filled cements are increasingly used in dental restorations.
  • Evaluating their biocompatibility and pulp response is crucial for clinical success.
  • Previous laboratory tests indicated promising performance for several resin cement formulas.

Purpose of the Study:

  • To assess the pulp reactions of resin-filled cements in primate models.
  • To compare the biocompatibility of resin cements against positive (silicate cement) and negative (zinc oxide-eugenol) controls.
  • To evaluate the effect of calcium hydroxide protection on resin cement-induced pulp responses.

Main Methods:

  • Primate models were used to evaluate pulp tissue reactions to different resin-filled cement formulations.
  • Three control groups were included: silicate cement (positive), zinc oxide-eugenol (negative), and calcium hydroxide protection.
  • Histological assessments were performed at 5-day, intermediate, and prolonged (60-day) evaluation periods.

Main Results:

  • Chemical cure resin cement exhibited the lowest pulp reactions at the 5-day evaluation.
  • No significant differences in pulp reactions were observed between resin cements and controls at intermediate and prolonged periods, with average, acceptable responses.
  • Resin cements, with or without calcium hydroxide, demonstrated favorable comparisons to the negative control (IRM) after 60 days, with minimal microleakage-associated microorganisms and no correlation to pulp inflammation.

Conclusions:

  • Resin-filled cements, when appropriately applied, are expected to be well-tolerated by human dental pulp.
  • The biocompatibility of resin cements is comparable to or better than traditional materials like zinc oxide-eugenol over time.
  • Calcium hydroxide does not negatively impact the pulp response to resin cements, showing typical, resolving reactions.

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