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Updated: Aug 23, 2026

Protocol and Guidelines for Point-of-Care Lung Ultrasound in Diagnosing Neonatal Pulmonary Diseases Based on International Expert Consensus
Published on: March 6, 2019
Cavitating tuberculosis in an infant: case report and literature review
Rob Van Hest1, Gerard De Vries, Giovanni Morbano
1Department of Tuberculosis Control, Municipal Health Service Rotterdam, the Netherlands. vanhestr@ggd.rotterdam.nl
Insights
Primary cavitating tuberculosis is a rare but serious condition in young children. Early diagnosis is crucial, especially when the source of infection is unknown, to prevent complications.
Area of Science:
- Pediatrics
- Infectious Diseases
- Radiology
Background:
- Primary tuberculosis (TB) is uncommon in infants.
- Primary cavitating tuberculosis is a rare complication of primary TB in children.
- Diagnosing childhood TB is challenging without a known adult contact.
Observation:
- An 8-month-old infant presented with primary cavitating tuberculosis.
- There was a significant delay in diagnosing the infant's condition.
- The case highlights diagnostic difficulties in pediatric TB.
Findings:
- The infant's condition represents a rare manifestation of primary TB.
- Delayed diagnosis can exacerbate the severity of pediatric TB.
- Literature review supports the rarity and diagnostic challenges of this condition.
Implications:
- Emphasizes the need for heightened clinical suspicion for TB in infants, even without clear exposure.
- Suggests improved diagnostic strategies are needed for pediatric TB.
- Underscores the importance of considering rare complications like cavitary disease in young children.
Abstract:
Primary cavitating tuberculosis is a rare complication of primary tuberculosis in young children. In the absence of a known adult source case, the diagnosis of tuberculosis in children can be difficult. We describe an 8-month-old baby with primary cavitating tuberculosis, in whom there was considerable delay in diagnosis, and review the literature.
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