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Updated: Aug 23, 2026

CO2-Lasertonsillotomy Under Local Anesthesia in Adults
Published on: November 6, 2019
[Amoxicillin in tonsillectomy: preliminary data on the evaluation of serum and tissue concentrations]
Gianluca Averono1, Massimo Olina, Matteo Basile
1Clinica Otorinolaringoiatrica, Università degli Studi del Piemonte Orien- tale Amedeo Avogadro, Novara.
Abstract:
Amoxicillin was administered to 50 patients with chronic recurrent tonsillitis waiting for tonsillectomy. Group A (N=16) received 2.2 g of amoxicillin plus clavulanic acid with intravenous injection 10 minutes before tonsillectomy Group B (N=34) was treated with 3 doses of amoxicillin-clavulanic acid administered orally the day before surgery, plus one oral administration 2 hours before tonsillectomy. Antibiotic doses were established on patient's weight using maximum suggested. The measures were, estimated in serum and in tonsils using High Performance Liquid Chromatography, (HPLC). The data show better efficacy of intravenous administration than oral administration.
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