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Updated: Aug 7, 2026

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
Published on: February 26, 2013
[Atrial lead placement in the right atrial appendage during recent or chronic arrhythmia]
F Raybaud1, J P Camous, D Cauchy
1Service de cardiologie, hôpital Pasteur, Nice.
Insights
Placing atrial leads during an atrial arrhythmia is feasible and shows good performance at six months. This approach ensures satisfactory atrial pacing and preserves atrioventricular synchrony in patients with sinus rhythm.
Area of Science:
- Cardiology
- Electrophysiology
- Medical Devices
Context:
- Atrial arrhythmias can complicate atrial lead implantation, potentially requiring delays or abandonment.
- Traditional approaches necessitate restoring sinus rhythm before lead placement.
- Investigating lead performance during arrhythmia is crucial for optimizing cardiac device therapy.
Purpose:
- To evaluate the feasibility and six-month performance of atrial lead placement during an active atrial arrhythmia.
- To assess lead parameters, including pacing thresholds and signal amplitude, in patients experiencing arrhythmias.
- To compare outcomes between recent-onset and chronic arrhythmias regarding lead performance.
Summary:
- A study of 65 patients (mean age 78.5 years) with sick sinus syndrome or heart block, who underwent atrial lead implantation in the right atrial appendage during atrial fibrillation, flutter, or tachycardia.
- Sinus rhythm was restored in most patients; those in sinus rhythm at one and six months demonstrated good atrial lead performance, with stable pacing thresholds and signal amplitudes.
- Lead performance and pacemaker function in DDD(R) mode were comparable between patients with recent and chronic arrhythmias at six months.
Impact:
- Demonstrates that atrial lead implantation during atrial arrhythmia is a viable strategy.
- Supports successful atrial-based pacing and maintenance of atrioventricular synchrony.
- Offers an alternative approach for patients with arrhythmias, potentially avoiding procedure delays or cancellations.
Abstract:
An atrial arrhythmia could be encountered during the atrial lead implantation. The lead placement must subsequently be delayed after restitution of the sinus rhythm or completely abandoned. The authors investigate the atrial lead placement during atrial arrhythmia and the lead performance at 6-month follow-up. The study population was 65 patients aged 78.5 years, 42 males and 28 structural heart diseases. They were implanted for sick sinus syndrome (n=14), atrioventricular block (n=44), infra-hisian conduction abnormality (n=7) in association with an atrial fibrillation (63.1%), an atrial flutter (24.6%) or an atrial tachycardia (12.3%). The onset of the arrhythmia was < or = 7 days (47.7%) or > 7 days (52.3%). An atrial lead was placed in the right atrial appendage under fluoroscopic control. If the sinus rhythm was not restored at 1 month, an electrical cardioversion was performed. The per-implantation atrial signal amplitude was 2.2+/-1.5 mV (range 0.5 mV to 7 mV). Sinus rhythm was restored in 54 patients. At 1 month, one patient was in an incessant atrial fibrillation. The 53 patients in sinus rhythm had a good atrial lead performance. Out of 46 patients who completed the 6-month follow-up, 4 had an arrhythmia recurrence. The 42 patients in sinus rhythm had a good atrial lead performance. At 1 and 6-month follow-up, the atrial pacing threshold (1.1+/-0.7 V vs 1.2+/-1.0 V, ns) and the atrial signal amplitude (2.1+/-1.0 mV and 2.1+/-0.9 mV, ns) were stable. Comparing the patients with a recent or a chronic arrhythmia, the pacing thresholds (1.2+/-1.1 V vs 1.14+/-0.8 V, ns), the atrial signal amplitudes (2.17+/-0.9 mV vs 2.05+/-0.9 mV, ns) and the proportion of satisfactory pacemaker performance in DDD(R) mode for the patients in sinus rhythm (100% vs 100%, ns) did not statistically differ between the two groups at 6 months. In conclusion, the placement of an atrial lead in the right atrial appendage during an atrial arrhythmia is feasible with a good lead performance at 6 months in sinus rhythm regardless the onset time of the arrhythmia and provides a satisfactory atrial-based pacing with the preservation of the atrioventricular synchrony.
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