Related Experiment Video
Updated: Aug 23, 2026

Quantitative Detection of DNA-Protein Crosslinks and Their Post-Translational Modifications
Published on: April 21, 2023
Protein recycling is a major component of post-irradiation recovery in Deinococcus radiodurans strain R1
Bhakti Joshi1, Roland Schmid, Karlheinz Altendorf
1Molecular Biology Division, Bhabha Atomic Research Centre, Mumbai 400085, India.
Abstract:
Exposure to 6kGy dose of (60)Co gamma-rays resulted in immediate growth arrest, followed by complete recovery of Deinococcus radiodurans strain R1 cells. Selective degradation and resynthesis of several predicted highly expressed proteins (including major chaperones, key TCA cycle enzymes, and few stress proteins) and several hypothetical proteins marked the lag period, preceding resumption of growth. A major exercise in protein recycling appears to be an integral component of post-irradiation recovery in D. radiodurans and complements the extensive DNA repair, characteristic of this extremely radioresistant bacterium.
Related Concept Videos
Other Unique Bacteria
Bioremediation
Microbial Bioremediation of Plastics
Regulation of the Unfolded Protein Response
Bioplastics
Homologous Recombination

