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Effects of thioacetamide on pancreatic islet B-cell function

Willy J Malaisse1, Philippe Lebrun, Abdullah Sener

  • 1Laboratories of Experimental Hormonology and Pharmacology, Brussels Free University, Brussels, Belgium. malaisse@ulb.ac.be

Endocrine
|July 14, 2004
PubMed
Summary

Thioacetamide treatment impairs insulin secretion in rats by affecting calcium handling in pancreatic islet B-cells. This leads to reduced glucose oxidation and altered responses to secretagogues.

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