Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Hyperparathyroidism.

G Tonini1, L Tatò, F Rigon

  • 1Department of Pediatrics, University of Trieste, Trieste, Italy.

Minerva Pediatrica
|July 14, 2004
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A low-dose multicomponent medication as a new approach in prevention and early add-on treatment of recurrent respiratory infections in children: a Delphi Consensus.

European review for medical and pharmacological sciences·2024
Same author

Safety and effectiveness of a somatropin biosimilar in children requiring growth hormone treatment: second analysis of the PATRO Children study Italian cohort.

Journal of endocrinological investigation·2020
Same author

The microRNA-29a Modulates Serotonin 5-HT7 Receptor Expression and Its Effects on Hippocampal Neuronal Morphology.

Molecular neurobiology·2019
Same author

Infantile swallowing: surgical meaning.

La Clinica terapeutica·2019
Same author

Evaluation of growth hormone response to GHRH plus arginine test in children with idiopathic short stature: role of peak time.

Journal of endocrinological investigation·2018
Same author

Can Type 1 diabetes progression be halted? Possible role of high dose vitamin D and omega 3 fatty acids.

European review for medical and pharmacological sciences·2017
Same journal

Developmental and behavioral profile in a domestic adoptees sample: a new challenge for the pediatrician.

Minerva pediatrica·2020
Same journal

A new approach to the diagnosis of short stature.

Minerva pediatrica·2020
Same journal

Management of the main endocrine and diabetic disorders in children.

Minerva pediatrica·2020
Same journal

Kounis Syndrome: a pediatric perspective.

Minerva pediatrica·2020
Same journal

Human inborn errors of immunity caused by defects of receptor and proteins of cellular membrane.

Minerva pediatrica·2020
Same journal

Tall stature in children and adolescents.

Minerva pediatrica·2020
See all related articles

Hyperparathyroidism involves high calcium and low phosphate due to excess parathyroid hormone (PTH). Treatment focuses on hydration, calciuresis, and addressing the underlying cause.

Area of Science:

  • Endocrinology
  • Pediatric Endocrinology
  • Nephrology

Background:

  • Hyperparathyroidism is characterized by hypercalcemia and hypophosphatemia due to elevated parathyroid hormone (PTH) secretion.
  • It presents in three forms: primary, secondary, and tertiary, with primary hyperparathyroidism being rare in children.
  • Symptoms range from asymptomatic to severe, including anorexia, dehydration, altered growth, and potentially life-threatening hypercalcemia.

Purpose of the Study:

  • To provide a comprehensive overview of hyperparathyroidism, including its classification, clinical manifestations, and management strategies.
  • To highlight the specific challenges in diagnosing and treating hyperparathyroidism in pediatric populations.
  • To outline emergency treatment protocols for severe hypercalcemia and discuss the management of secondary and tertiary forms.

Related Experiment Videos

Main Methods:

  • Literature review and synthesis of existing knowledge on hyperparathyroidism.
  • Analysis of clinical presentations, diagnostic criteria, and treatment approaches.
  • Categorization of hyperparathyroidism into primary, secondary, and tertiary forms based on etiology and pathophysiology.

Main Results:

  • Primary hyperparathyroidism is uncommon in children, with hyperplasia often seen in neonates and infants.
  • Severe hypercalcemia (>13.5 mg/dl) can lead to significant complications affecting multiple organ systems.
  • Secondary hyperparathyroidism is associated with chronic hypocalcemia (e.g., renal failure, vitamin D deficiency), while tertiary hyperparathyroidism involves autonomous parathyroid glands.

Conclusions:

  • Effective management of hyperparathyroidism requires prompt diagnosis and a multi-faceted treatment approach.
  • Emergency treatment for severe hypercalcemia is critical to prevent organ damage.
  • Understanding the distinct etiologies of primary, secondary, and tertiary hyperparathyroidism is essential for targeted therapy.