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Atrophic dermatofibrosarcoma protuberans: an uncommon and misleading variant
Jason K Wu1, Mohsin M Malik, Conleth Anthony Egan
1Department of Dermatology, Our Lady of Lourdes Hospital, Drogheda, Louth, Ireland. jasonkwu@hotmail.com
The Australasian Journal of Dermatology
|July 15, 2004
Summary
Dermatofibrosarcoma protuberans, a rare skin cancer, can initially mimic benign conditions like morphoea. Early recognition of its subtle growth is crucial for timely diagnosis and treatment.
Area of Science:
- Dermatopathology
- Oncology
- Surgical Pathology
Background:
- Dermatofibrosarcoma protuberans (DFSP) is a rare, locally aggressive skin cancer.
- DFSP can present with subtle clinical features, often mimicking benign dermatoses.
- Delayed diagnosis of DFSP can lead to increased tumor size and complexity of treatment.
Observation:
- A 23-year-old male presented with a long-standing atrophic shoulder lesion.
- Initial biopsy suggested a fibrohistiocytic origin; clinical appearance resembled morphoea or atrophoderma.
- The lesion demonstrated slight growth over a 15-month observation period.
Findings:
- Repeat biopsy confirmed dermatofibrosarcoma protuberans (DFSP).
- Histopathology revealed a storiform spindle cell proliferation with positive CD34 staining.
- Surgical excision with a 3-cm margin was performed.
Implications:
- This case highlights a rare presentation of DFSP mimicking benign skin conditions.
- Increased awareness of such presentations can aid in earlier diagnosis of DFSP.
- Prompt diagnosis and complete surgical excision are essential for managing DFSP effectively.