Related Experiment Video
Updated: Aug 10, 2026

09:53
Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery
Published on: July 5, 2021
[Echographic differential diagnosis in oculo-orbital tumors]
Summary
This study evaluated 130 patients, diagnosing 25 with oculo-orbital tumors using clinical exams and adapted ultrasonography. A novel, rapid morphopathological method involving formaldehyde fixation was also proposed for tumor diagnosis.
Area of Science:
- Ophthalmology
- Oncology
- Medical Imaging
Background:
- Oculo-orbital tumors present a diagnostic challenge.
- Accurate and timely diagnosis is crucial for effective treatment planning.
Purpose of the Study:
- To assess the diagnostic utility of clinical examination and ultrasonography in oculo-orbital tumors.
- To introduce a simplified morphopathological technique for tumor diagnosis.
Main Methods:
- Clinical examination and ultrasonography (using adapted Bruel and Kjaer 3405 and Shimasonic devices) were performed on 130 patients.
- Diagnosis was further refined using fluorescein angiography, radiotracer studies, and morphopathological examinations.
- A novel method of formaldehyde fixation for 48 hours was proposed for pathological assessment.
Main Results:
- Out of 130 patients, 25 were diagnosed with various types of oculo-orbital tumors.
- The adapted ultrasonography provided valuable diagnostic information.
- The proposed formaldehyde fixation method offers a fast and simple approach to morphopathology.
Conclusions:
- Clinical examination and adapted ultrasonography are effective tools for diagnosing oculo-orbital tumors.
- The proposed 48-hour formaldehyde fixation method is a practical advancement in morphopathological diagnosis of these tumors.

