[The microbial flora in septic corneal ulcers]

M Oprescu1, G Strejaru

  • 1Clinica Oftalmologică Craiova.

Oftalmologia (Bucharest, Romania : 1990)
|April 1, 1992
PubMed

Insights

Microbial analysis of 101 corneal ulcers revealed Staphylococcus aureus as the most frequent pathogen. Researchers emphasize investigating lacrimal pathway permeability to identify the primary source of corneal infections.

Area of Science:

  • Ophthalmology
  • Microbiology

Context:

  • Septic corneal ulcers represent a significant cause of vision impairment.
  • Understanding the microbial etiology is crucial for effective treatment.

Purpose:

  • To identify the predominant microbial pathogens in septic corneal ulcers.
  • To highlight the importance of assessing lacrimal pathway integrity in corneal infections.

Summary:

  • Analysis of 101 corneal ulcer cases identified gram-positive bacteria as the most common cause, with Staphylococcus aureus (golden Streptococcus) in 83 cases.
  • Other identified gram-positive bacteria include Streptococcus (7 cases), Pneumococcus (2 cases), and gram-positive Bacillus (14 cases).
  • Gram-negative bacteria such as Moraxella (7 cases), Proteus (4 cases), Klebsiella (2 cases), Pseudomonas (2 cases), and Enterobacter (1 case) were also detected.

Impact:

  • This research underscores the need for comprehensive microbial investigations in corneal ulcer cases.
  • It emphasizes the critical role of evaluating lacrimal pathway permeability as a potential source of infection, guiding diagnostic and therapeutic strategies.

Related Concept Videos

Surface Membrane Barriers01:18

Surface Membrane Barriers

The skin and mucous membranes serve as the primary line of defense against pathogens by providing both physical and chemical protection. These barriers are essential in preventing the entry and establishment of microbes, thereby maintaining the integrity of the host.
The outer layer of the skin, the epidermis, is a robust barrier comprising layers of closely packed keratinized cells. This dense arrangement prevents microbes from penetrating the body. The periodic shedding of epidermal cells...
Microbial Corrosion01:24

Microbial Corrosion

Microbiologically Influenced Corrosion (MIC) is a significant form of material degradation caused by the metabolic activities of microorganisms. This phenomenon poses substantial challenges across various industries, including oil and gas, maritime, and water treatment sectors.MIC occurs when microorganisms, such as bacteria, archaea, and fungi, colonize metal surfaces, forming biofilms that alter the local electrochemical environment. These biofilms can lead to the production of corrosive...
The Skin Microbiota01:27

The Skin Microbiota

The human skin serves as a complex ecosystem inhabited by a diverse community of microorganisms, including bacteria, fungi, and viruses. This microbiome plays a critical role in maintaining skin health and defending against pathogenic invaders. The composition of microbial communities varies significantly across different regions of the body, influenced primarily by the local levels of moisture and sebum.Regional Variation in Skin MicrobiotaCutibacterium acnes predominantly colonizes sebaceous...
Microbiome of the Eye01:22

Microbiome of the Eye

The human eye has a specialized microbiota that reflects its unique anatomical and immunological environment. This low-biomass microbial community predominantly colonizes the conjunctiva and eyelid margins, playing a vital role in ocular surface homeostasis and defense. Despite its proximity to the richly colonized facial skin, the ocular surface maintains a distinct microbial profile due to continuous mechanical and biochemical defense mechanisms.The conjunctival surface hosts fewer microbial...
Microbiota of the Respiratory Tract01:29

Microbiota of the Respiratory Tract

The human respiratory tract, comprising the upper and lower segments, serves as a critical interface with the external environment. The upper respiratory tract (URT)—including the nostrils, sinuses, pharynx, and oropharynx—is heavily colonized by microbes, while the lower respiratory tract (LRT), composed of the larynx, trachea, bronchi, and lungs, was long thought to be sterile. However, recent molecular studies have revealed that the lungs are not devoid of microbes but act more like...
Microbiota of the Urogenital Tract01:28

Microbiota of the Urogenital Tract

The human urogenital system, once thought to be sterile in healthy individuals, is now recognized as a complex microbial habitat. Advancements in molecular sequencing techniques have revealed that even in healthy adults, the kidneys and bladder harbor microbial populations similar to those found in the distal urethra, albeit in much lower abundance. These resident microorganisms, while generally innocuous, can become opportunistic pathogens under conditions that alter the urogenital...