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Related Experiment Videos

Has fine-needle aspiration biopsy changed thyroid practice?

M Hadi1, H Gharib, J R Goellner

  • 1Division of Endocrinology/Metabolism and Internal Medicine, Mayo Clinic and Mayo Foundation, Rochester, Minnesota.

Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists
|January 1, 1997
PubMed
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Fine-needle aspiration (FNA) biopsy significantly improved thyroid nodule management by increasing cancer detection rates and reducing unnecessary surgeries. This led to better patient selection and cost savings in thyroid practice.

Area of Science:

  • Endocrinology
  • Surgical Oncology
  • Diagnostic Cytopathology

Background:

  • Nodular thyroid disease management relies on accurate diagnostic tools.
  • Fine-needle aspiration (FNA) biopsy is a key diagnostic procedure.

Purpose of the Study:

  • To evaluate the impact of fine-needle aspiration (FNA) biopsy introduction on thyroid surgical practice.
  • To assess changes in patient selection and diagnostic yield for nodular thyroid disease.

Main Methods:

  • Retrospective analysis of thyroid surgical data from two periods: pre-FNA (1975-1976) and post-FNA (1985-1986).
  • Comparison of patient numbers undergoing thyroidectomy and carcinoma detection rates before and after FNA implementation.

Main Results:

Related Experiment Videos

  • Thyroidectomy rates decreased significantly post-FNA introduction (938 vs. 513 patients).
  • Carcinoma yield in thyroidectomy specimens increased from 18% to 25% (P<0.0001).
  • Selecting patients based on "suspicious" or malignant FNA results yielded a 40% carcinoma rate.

    • Conclusions:

    • FNA biopsy enhances surgical selectivity for nodular thyroid disease.
    • FNA reduces thyroidectomies for benign conditions, increasing the detection of malignant lesions.
    • FNA biopsy offers substantial cost-saving benefits for thyroid practice.