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Hypertension in elderly persons.

B P Hamilton1, J H Hamilton

  • 1Department of Medicine, Baltimore VA Medical Center, Baltimore, Maryland 21201, USA.

Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists
|January 1, 1997
PubMed
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Hypertension is common in older adults, with over half of whites and three-quarters of African-Americans aged 60-74 affected. Effective drug treatments, particularly thiazide diuretics and beta-blockers, reduce cardiovascular risks when lifestyle changes are insufficient.

Area of Science:

  • Gerontology
  • Cardiovascular Medicine
  • Pharmacology

Background:

  • Hypertension prevalence significantly increases with age.
  • Managing blood pressure in elderly individuals is crucial for preventing cardiovascular events.

Purpose of the Study:

  • To summarize hypertension prevalence in the elderly.
  • To review antihypertensive drug classes, their benefits, and drawbacks.

Main Methods:

  • Literature review of clinical trials in elderly hypertensive patients.
  • Analysis of adverse reactions to antihypertensive therapies.

Main Results:

  • High hypertension rates observed: nearly 75% of African-Americans and 50% of whites aged 60-74.
  • Lifestyle modifications are primary; drug therapy is indicated if ineffective.

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  • Antihypertensive treatment significantly reduces cardiovascular mortality and stroke.
  • Low-dose thiazide diuretics and beta-blockers are recommended first-line agents with acceptable toxicity.
  • Conclusions:

    • Established effectiveness of hypertension treatment in elderly subjects.
    • Initiate drug therapy at low doses.
    • Close monitoring for adverse effects is essential.