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Microalbuminuria in type II diabetes
1Department of Surgery, Case Western Reserve University School of Medicine, and MetroHealth Medical Center, Cleveland, Ohio, USA.
Summary
Microalbuminuria, an early sign of kidney damage in type II diabetes, predicts cardiovascular disease and kidney failure. Prompt intervention with blood glucose control and blood pressure medication is crucial.
Area of Science:
- Nephrology
- Endocrinology
- Cardiology
Background:
- Microalbuminuria is a significant indicator in patients with type II diabetes.
- It signifies early-stage kidney damage and increased cardiovascular risk.
Purpose of the Study:
- To highlight the prognostic importance of microalbuminuria in type II diabetes.
- To review interventions for diabetic nephropathy.
Main Methods:
- Definition and implications of microalbuminuria were reviewed.
- Published intervention trials for proteinuria in type II diabetes were outlined.
Main Results:
- Microalbuminuria (30-300 mg protein/24h or 20-200 mg/min) is common in type II diabetes.
- It's an independent cardiovascular risk factor and predictor of renal failure.
- Interventions like tight glucose control and ACE inhibitors may reverse proteinuria or slow renal failure progression.
Conclusions:
- Microalbuminuria in type II diabetes is linked to premature cardiovascular death and renal failure.
- Aggressive therapeutic strategies are warranted.