Related Experiment Video
Updated: Aug 9, 2026

Intracoronary Acetylcholine Provocation Testing for Assessment of Coronary Vasomotor Disorders
Published on: August 18, 2016
A case of the Carney triad
1Division of Endocrinology, Diabetes and Metabolism, Jefferson Medical College of Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, USA.
Objective:
To report a case of mediastinal paraganglioma in the setting of the Carney triad (gastric leiomyosarcoma, extra-adrenal paraganglioma, and pulmonary chondroma).
Methods:
A case of the Carney triad is presented, and the related literature is discussed.
Results:
A 47-year-old woman with a history of gastric leiomyosarcoma and retroperitoneal paraganglioma sought medical attention because of progressive shortness of breath. She was found to have a mediastinal mass in the aortopulmonary window. The patient had normal blood pressure and normal urinary catecholamines, but metaiodobenzylguanidine scintigraphy showed an intense uptake in the region of the mass, consistent with paraganglioma. She subsequently underwent resection of the mediastinal mass, and the surgical pathology report indicated paraganglioma.
Conclusion:
Patients with the Carney triad can have multicentric paragangliomas. Metaiodobenzylguanidine scanning may be helpful in the diagnostic workup.
Related Concept Videos
Coronary Artery Disease III: Clinical Manifestations
Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations
Acute Coronary Syndrome III: Diagnostic Studies
Cardiomyopathy II: Dilated Cardiomyopathy
Cardiomyopathy III: Hypertrophic Cardiomyopathy
Cardiomyopathy IV: Restrictive Cardiomyopathy
