Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Gender ambiguity in an elderly man.

V V Menghini1, J M Evans

  • 1Mayo Graduate School of Medicine, Mayo Clinic and Mayo Foundation, Rochester, Minnesota, USA.

Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists
|July 15, 2004
PubMed
Summary

A 72-year-old man with a history of hypospadias was found to have ovaries, uterus, and a 46,XX karyotype during surgery for colon cancer. This rare case of ambiguous genitalia in an elderly patient presents unique ethical considerations.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The Functional Medicine Approach to COVID-19: Virus-Specific Nutraceutical and Botanical Agents.

Integrative medicine (Encinitas, Calif.)·2020
Same author

The Functional Medicine Approach to COVID-19: Primer on SARS-CoV-2 Testing.

Integrative medicine (Encinitas, Calif.)·2020
Same author

A multi-method review of home-based chemotherapy.

European journal of cancer care·2015
Same author

Association of DLA-DQB1 alleles with exocrine pancreatic insufficiency in Pembroke Welsh Corgis.

Animal genetics·2015
Same author

13-Year experience in external fixation of the pelvis: complications, reduction and removal.

European journal of trauma and emergency surgery : official publication of the European Trauma Society·2015
Same author

Open distal tibial shaft fractures: a retrospective comparison of medial plate versus nail fixation.

European journal of trauma and emergency surgery : official publication of the European Trauma Society·2015

Area of Science:

  • Medicine
  • Genetics
  • Endocrinology

Background:

  • Ambiguous genitalia (AG) is a congenital condition affecting sexual development.
  • Diagnosis in elderly individuals is exceptionally rare, posing unique clinical and ethical challenges.

Purpose of the Study:

  • To report a unique case of an elderly male patient diagnosed with ambiguous genitalia.
  • To explore the etiologic factors and late-life consequences of this diagnosis.
  • To discuss the ethical implications of diagnosing AG in an elderly patient.

Main Methods:

  • Case report of a 72-year-old male patient undergoing hemicolectomy for colon cancer.
  • Intraoperative discovery of female reproductive organs (ovaries, uterus).
  • Postoperative karyotyping revealed a 46,XX chromosomal complement.

Related Experiment Videos

Main Results:

  • A 72-year-old male patient with a history of hypospadias and hypogonadism was found to possess internal female reproductive organs.
  • The patient's karyotype was determined to be 46,XX.
  • The diagnosis of ambiguous genitalia was established late in life.

Conclusions:

  • Diagnosing ambiguous genitalia in elderly patients is uncommon and presents significant ethical dilemmas.
  • Physicians must balance patient autonomy with the potential for psychologic harm.
  • This case highlights the importance of considering rare diagnoses even in advanced age.