Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Thyroid hormones and illness.

M D Brennan1, R S Bahn

  • 1Division of Endocrinology, Department of Internal Medicine, Mayo Clinic and Mayo Foundation, Rochester, Minnesota 55905, USA.

Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists
|July 15, 2004
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Current Insights into the Pathogenesis of Graves' Ophthalmopathy.

Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme·2015
Same author

Autoimmunity and Graves' disease.

Clinical pharmacology and therapeutics·2012
Same author

Depressive relapse during lithium treatment associated with increased serum thyroid-stimulating hormone: results from two placebo-controlled bipolar I maintenance studies.

Acta psychiatrica Scandinavica·2009
Same author

Professionalism and academic medicine: the Mayo Clinic program in professionalism.

Irish journal of medical science·2007
Same author

TSH receptor expression in orbital tissue and its role in the pathogenesis of Graves' ophthalmopathy.

Journal of endocrinological investigation·2004
Same author

High throughput genotyping technologies for pharmacogenomics.

American journal of pharmacogenomics : genomics-related research in drug development and clinical practice·2002
Same journal

Tirzepatide versus conventional GLP-1 receptor agonists for treatment simplification in type 2 diabetes mellitus: a real-world study.

Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·2026
Same journal

Risk-stratification of pediatric thyroid nodules using ATA and ACR TIRADS adult thyroid nodule scoring systems.

Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·2026
Same journal

Effectiveness of GLP-1 receptor agonists and SGLT-2 inhibitors combination therapy in type 2 diabetes: a real world experience.

Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·2026
Same journal

North American Society for Interventional Thyroidology (NASIT) Statement on Directed Ablative Therapy for the Management of of Low Risk Papillary Thyroid Carcinoma.

Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·2026
Same journal

Lower Cutoffs Improve the Diagnostic Performance of DDAVP-Stimulated Bilateral Inferior Petrosal Sinus Sampling for Cushing Disease: A Prospective Cohort Study.

Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·2026
Same journal

Efficacy of Initiation of Semaglutide versus SGLT2 inhibitors in Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD): A Multicenter Propensity-Matched Real-World Study.

Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·2026
See all related articles

Illness can alter thyroid hormone levels, affecting metabolism and transport. These changes, including decreased triiodothyronine production, are usually beneficial but require careful interpretation of thyroid tests in hospitalized patients.

Area of Science:

  • Endocrinology
  • Metabolic Medicine
  • Neuroendocrinology

Background:

  • Thyroid hormones are crucial for regulating metabolism and bodily functions.
  • Illness can significantly impact thyroid hormone levels, affecting patient outcomes.
  • Understanding these alterations is key to managing critically ill patients.

Purpose of the Study:

  • To review illness-associated changes in thyroid hormone levels.
  • To examine alterations in thyroid hormone metabolism, regulation, and transport during illness.
  • To assess the potential utility of thyroid hormone treatment in severe illness.

Main Methods:

  • Summarized normal pituitary-thyroid function.
  • Categorized thyroid hormone changes observed during illness.

Related Experiment Videos

  • Examined metabolic status and treatment utility in ill patients.

    • Main Results:

    • Illness-associated thyroid hormone alterations are adaptive responses.
    • Changes include decreased triiodothyronine production, reduced serum binding, and suppressed thyrotropin secretion.
    • These hormonal shifts offer insights into thyroid regulation and neuroendocrine adaptation.

    Conclusions:

    • Illness-induced thyroid hormone changes are generally beneficial.
    • Potential for localized tissue hypothyroidism exists.
    • Caution is advised when interpreting thyroid tests in hospitalized patients; further trials are needed for treatment efficacy.