Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Amiodarone-induced hyperthyroidism and a thyroid nodule.

C N Morris1, G H Tan, S A Smith

  • 1Division of Infectious Disease & Internal Medicine, Columbia Presbyterian Medical Center, New York, NY, USA.

Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists
|July 15, 2004
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Association of PRKCA expression and polymorphisms with layer duck eggshell quality.

British poultry science·2020
Same author

Preferential Use of Carbon Sources in Culturable Aerobic Mesophilic Bacteria of Coptotermes curvignathus's (Isoptera: Rhinotermitidae) Gut and Its Foraging Area.

Environmental entomology·2015
Same author

Breast Cancer Outcomes as Defined by the Estrogen Receptor, Progesterone Receptor, and Human Growth Factor Receptor-2 in a Multi-ethnic Asian Country.

World journal of surgery·2015
Same author

The Will Rogers phenomenon in the staging of breast cancer - does it matter?

Cancer epidemiology·2014
Same author

Prediction of lymph node involvement in patients with breast tumors measuring 3-5 cm in a middle-income setting: the role of CancerMath.

World journal of surgery·2014
Same author

Trace monitoring of water-borne phenolics in the Klang River Basin.

Environmental monitoring and assessment·2013
Same journal

Effect of Blood Donation in the Glycemic Control of Prediabetic Donors: A Blinded Randomized Controlled Trial.

Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·2026
Same journal

Etomidate in Severe Cushing Syndrome: An Underutilized Bridge in Endocrine Emergency Care.

Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·2026
Same journal

Insights from secular trend of major osteoporotic fractures in people with and without diabetes: 15-year population-based study (2009 - 2023).

Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·2026
Same journal

Early Metabolic Risk in Childhood Brain Cancer Survivors with Childhood-Onset Growth Hormone Deficiency.

Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·2026
Same journal

The Use of Directed Ablative Techniques for Autonomously Functioning Thyroid Nodules: A Statement from the North American Society for Interventional Thyroidology.

Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·2026
Same journal

North American Society for Interventional Thyroidology (NASIT) Statement on Directed Ablative Therapy for the Management of Cervical Recurrence of Papillary Thyroid Cancer.

Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·2026
See all related articles

Amiodarone therapy can cause thyrotoxicosis (overactive thyroid). Thyroid nodules require specific preoperative scanning to guide surgical treatment for amiodarone-induced hyperthyroidism.

Area of Science:

  • Endocrinology
  • Cardiology
  • Nuclear Medicine

Background:

  • Amiodarone is an effective antiarrhythmic drug.
  • Amiodarone therapy is associated with thyroid dysfunction, including thyrotoxicosis.
  • Thyroid nodules can complicate the management of amiodarone-induced thyrotoxicosis.

Purpose of the Study:

  • To present two cases of thyrotoxicosis linked to amiodarone.
  • To discuss how thyroid nodules influence the management of amiodarone-induced thyrotoxicosis.

Main Methods:

  • Case report of two patients with amiodarone-induced hyperthyroidism.
  • Review of the underlying mechanisms of amiodarone-induced thyrotoxicosis.
  • Development of a decision-making strategy for managing patients with thyroid nodules.

Related Experiment Videos

Main Results:

  • Amiodarone-induced thyrotoxicosis results from direct toxicity or excess iodine.
  • Surgical intervention may be necessary when amiodarone discontinuation or medical management fails.
  • Preoperative thyroid scanning is crucial to differentiate between a hyperfunctioning nodule and diffuse disease, guiding surgical extent.

Conclusions:

  • Preoperative thyroid scanning is essential for surgical planning in amiodarone-induced hyperthyroidism with a solitary thyroid nodule.
  • Findings guide surgeons to perform subtotal thyroidectomy for diffuse disease or lobectomy for a hyperfunctioning nodule.