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Updated: Aug 23, 2026

Chronic Intermittent Ethanol Vapor Exposure Paired with Two-Bottle Choice to Model Alcohol Use Disorder
Published on: June 23, 2023
Recent advances in cyclic-adenosine monophosphate/protein kinase A signaling in ethanol-induced synaptic and
L Judson Chandler1, Antonello Bonci, Gary S Wand
1Alcohol Research Center and Department of Physiology/Neuroscience, Medical University of South Carolina, Charleston, South Carolina 29425, USA. chandj@musc.edu
Abstract:
This article represents the proceedings of a symposium at the 2002 RSA Meeting in San Francisco, California, organized and co-chaired by L. Judson Chandler and Richard A. Morrisett. The presentations were (1) PKA regulates chronic ethanol-induced synaptic targeting of NMDA receptors, by L. Judson Chandler; (2) Long-lasting potentiation of GABAergic synapses in dopamine neurons after a single in vivo ethanol exposure, by Antonello Bonci; (3) The DARPP-32 cascade and regulation of the ethanol sensitivity of NMDA receptors in the nucleus accumbens, by Richard A. Morrisett; (4) and The cAMP/PKA signal transduction pathway modulates ethanol consumption and sedative effects of ethanol, by Gary S. Wand.
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