Related Experiment Videos
Increasing occurrence of urological cancers in Slovakia
I Plesko1, A Obsitnikova, M Cuninkova
1National Cancer Registry of Slovakia, National Cancer Institute, Bratislava, Slovak Republic. plesko@adamsoft.sk
Neoplasma
|July 16, 2004
Summary
Urological cancer incidence and mortality are rising in Slovakia, particularly for prostate and kidney cancers. Testicular cancer shows a notable mortality reduction despite increased incidence.
Area of Science:
- Urology
- Oncology
- Public Health
Background:
- Urological cancers represent a significant and increasing health burden globally and in Slovakia.
- These cancers disproportionately affect men, accounting for 17% of new diagnoses worldwide, compared to 3% in women.
Purpose of the Study:
- To analyze temporal trends in the incidence and mortality of upper and lower urinary tract cancers in Slovakia.
- To evaluate the effectiveness of current cancer control measures and identify areas for future intervention.
Main Methods:
- Utilized data from the National Cancer Registry (1968-1999) for incidence and the Statistical Office of the Slovak Republic for mortality.
- Employed age-adjustment using the world standard population and Poisson regression for trend analysis, calculating mean annual percent changes (MACP).
Main Results:
- Prostate cancer incidence and mortality showed substantial, parallel increases.
- Testicular cancer incidence dramatically increased, yet mortality remained stable with a recent downward trend.
- Urinary bladder cancer incidence rose in women, while men's rates peaked; kidney cancer incidence increased in both sexes with slow mortality rises.
- All analyzed trends were statistically significant, except for testicular cancer mortality.
Conclusions:
- Testicular cancer is the only malignancy with significant mortality reduction despite rising incidence.
- Smoking reduction and improved industrial hygiene may impact bladder cancer trends.
- Limited resources hinder the development of comprehensive cancer control programs, projecting continued increases in prostate and kidney cancer incidence and mortality in Slovakia.