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Updated: Aug 23, 2026

Surgical Treatment of an Endolymphatic Sac Tumor
Published on: May 26, 2023
Endodermal sinus tumor of the parotid gland in a child
Simone Treiger Sredni1, Isabela Werneck da Cunha, Nevigolino Pereira de Carvalho Filho
1Department of Pathology, Hospital do Cancer, Rua Professor Antonio Prudente 211, São Paulo 01 509-900, Brazil. ssredni@ludwig.org.br
Abstract:
We report a case of a 16-month-old girl with a primary endodermal sinus tumor (EST) of the parotid gland. The girl was admitted to the hospital with a left side cervical tumor with a quick growth (within 3 wk). The tumor was surgically resected. The gross examination showed a 7.0-cm hemorrhagic and fragmentized mass. Diagnosis of an EST was established on the hematoxylin and eosin-stained slides from the resected material. Elevated serum alpha-fetoprotein (AFP) levels were detected and follow-up examinations of the patient did not show ESTs in other locations or other manifestations due to the tumor. The patient received chemotherapy after the surgery and remained alive without evidence of disease at the time of this writing (2 years after the diagnosis). As far as we know, this is the second report in the literature of a parotid gland's EST.
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