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Updated: Aug 23, 2026

Establishment and Propagation of Human Retinoblastoma Tumors in Immune Deficient Mice
Published on: August 4, 2011
A second primary tumor in a patient with retinoma
Lindy-Anne Korswagen1, Annette C Moll, Saskia M Imhof
1Department of Ophthalmology, VU University Medical Center, Amsterdam, The Netherlands.
Aim:
To evaluate the frequency of the co-occurrence of a retinoma and another primary tumor.
Method:
Presentation of a case report and review of the literature.
Results:
A cutaneous melanoma was observed in a 52-year-old man, who was known to have two retinomas in the right eye. Five other cases were found in a review of the literature, suggesting the possibility of an increased risk of developing a second primary tumor in patients with retinoma. The occurrence of cutaneous melanoma as a second primary tumor after retinoma and/or retinoblastoma is discussed.
Conclusion:
There might be an increased risk for patients with retinoma to develop another primary tumor, necessitating regular follow-up of these patients.
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