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Updated: Aug 23, 2026

Comprehensive Protocol to Sample and Process Bone Marrow for Measuring Measurable Residual Disease and Leukemic Stem Cells in Acute Myeloid Leukemia
Published on: March 5, 2018
[Early diagnosis of leukaemia in the trisomic child. Congolese experience based on two cases]
A Mouko1, F Nkanta-Etokabeka, P Senga
1Service de pédiatrie Nourrissons, CHU, Brazzaville, BP32, République du Congo.
Abstract:
We are reporting here two cases of acute leukemia in Congolese children with Down syndrome. They were aged 27 and 30 months. The two cases were revealed by anemia, hyperthermia with enlargement of the liver and the spleen. Clinical course was unfavorable. Therefore, the early diagnosis of leukemia remains very important in patient with Down syndrome presenting hyperthermia with hepatosplenomegaly.
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