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Hepatic infarction following abdominal interventional procedures
Hiroyasu Fujiwara1, Susumu Kanazawa, Takao Hiraki
1Department of Radiology, Okayama University Graduate School of Medicine and Dentistry, Okayama 700 8558, Japan. fuji@cc.okayama-u.ac.jp
Insights
Hepatic infarction, a rare but fatal complication of interventional procedures, occurred in 0.5% of cases. Emergency embolization for hemorrhagic shock was a frequent cause.
Area of Science:
- Interventional Radiology
- Hepatology
- Vascular Surgery
Background:
- Hepatic infarction is a serious complication following interventional procedures.
- Understanding its incidence and risk factors is crucial for patient safety.
Purpose of the Study:
- To determine the incidence, background, and progression of hepatic infarction after interventional procedures.
- To identify risk factors and outcomes associated with post-interventional hepatic infarction.
Main Methods:
- Retrospective review of 1982 abdominal angiography and interventional procedures.
- Analysis of clinical records and abdominal CT scans for hepatic infarction.
- Identification of nine cases of hepatic infarction over a decade.
Main Results:
- Nine episodes (0.5%) of hepatic infarction were identified in 8 patients.
- Commonly associated with emergency embolization for postoperative bleeding and hemorrhagic shock.
- Hepatic arterial occlusion and portal venous flow abnormalities were observed.
- Impaired baseline liver function correlated with mortality, not CT findings.
Conclusions:
- Hepatic infarction following interventional procedures is rare but can be fatal.
- Emergency embolization in hemorrhagic shock is a significant risk factor.
- Multiple risk factors, including arterial insufficiency, contribute to its occurrence.
Abstract:
To clarify the incidence, background, and progress of hepatic infarction following interventional procedures, cases of hepatic infarction following interventional procedures at our department during the last decade were identified by reviewing the clinical records of 1982 abdominal angiography and interventional procedures and records of abdominal CT. Nine episodes (0.5%) in 8 patients were identified as hepatic infarction following an interventional procedure. Five episodes were preceded by embolization of the hepatic or celiac artery at emergency angiography for postoperative bleeding with hemorrhagic shock. Three episodes followed the elected interventional procedure for hepatocellular carcinoma, and the remaining episode occurred after 12 months of chemoinfusion through an indwelling catheter in the hepatic artery and portal vein. Hepatic arterial occlusion in all episodes and portal venous flow abnormality in 5 episodes were observed on angiography. Four patients whose liver function was initially impaired died of hepatic infarction, although the extent of the disease on CT did not appear to be related to the mortality. Multiple risk factors, including arterial insufficiency, were observed in each patient. The incidence of hepatic infarction following interventional procedures in this series was low but sometimes fatal, and occurred most frequently in emergency embolization in hemorrhagic shock.
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