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Related Experiment Videos

Do thyroid function tests independently predict survival in the critically ill?

L S Maldonado1, G H Murata, J M Hershman

  • 1Department of Medicine, Cedars-Sinai Medical Center, UCLA School of Medicine.

Thyroid : Official Journal of the American Thyroid Association
|January 1, 1992
PubMed
Summary
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Thyroid function tests can help predict survival in critically ill patients. Low triiodothyronine (T3) levels independently predicted nonsurvival, even beyond physician predictions.

Area of Science:

  • Endocrinology
  • Critical Care Medicine

Background:

  • Thyroid dysfunction is common in critically ill patients.
  • Predicting survival in critical illness is challenging.

Purpose of the Study:

  • To evaluate the predictive ability of thyroid function tests for hospital survival in critically ill patients.
  • To compare thyroid function test predictions with physician predictions.

Main Methods:

  • Studied 116 critically ill patients.
  • Assessed thyroid function tests (T3, FT3I, T4, FT4I, TSH, T3U).
  • Compared test results with hospital survival and physician predictions.

Main Results:

  • Hypothyroidism was present in 9.5% of patients and associated with lower survival.

Related Experiment Videos

  • In nonthyroidal illness, low T3, low FT3I, low T4, low FT4I, high TSH, and high T3U correlated with nonsurvival.
  • Low T3 and high TSH independently predicted nonsurvival.
  • Low T3 provided significant independent prediction beyond clinical physician assessment.

    • Conclusions:

    • Thyroid function tests, particularly low T3, can aid in predicting survival in critically ill patients.
    • Low T3 offers valuable prognostic information that complements clinical judgment.