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Related Concept Videos

Epilepsy and Seizures: Overview01:24

Epilepsy and Seizures: Overview

Epilepsy is a chronic neurological disease marked by recurrent, unpredictable seizures. These seizures are caused by abnormal electrical discharges in the brain, leading to behavior, sensation, or consciousness alterations. They can also cause transient impairment of awareness, interfering with daily activities.
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
Seizures: Classification01:13

Seizures: Classification

Epilepsy is primarily characterized by unpredictable seizures, either provoked by an identifiable factor, such as injury or illness, or unprovoked, occurring spontaneously without apparent cause.
Seizures are typically classified into two main categories: focal and generalized seizures.
Focal Seizures
Focal seizures originate from specific regions of the brain. These seizures are further sub-classified into two types:
Antiepileptic Drugs: Potassium Channel Activators01:20

Antiepileptic Drugs: Potassium Channel Activators

Ezocgabine or retigabine, an antiepileptic drug of remarkable efficacy, has revolutionized the management of seizures. It is a potassium channel activator, explicitly targeting the family of Q subtype potassium channels. It enhances the transmembrane potassium currents, regulating neuronal excitability. This action stabilizes the resting membrane potential, a pivotal factor in mitigating the hyperexcitability that characterizes epilepsy.
Ezogabine has gained approval as an adjunctive treatment...
Seizures l: Introduction01:20

Seizures l: Introduction

Understanding seizures and epilepsy relies on key definitions that help in recognizing, classifying, and managing these disorders. These definitions provide a framework for recognizing, classifying, and managing seizure disorders.DefinitionsA seizure is a sudden, abnormal burst of electrical activity in the brain that can cause changes in awareness, movement, sensation, or behavior, depending on the area involved. Epilepsy is a chronic condition characterized by recurrent, unprovoked seizures,...
Seizures ll: Types01:19

Seizures ll: Types

Seizures are sudden bursts of abnormal electrical discharge in the brain that interfere with normal function. They are commonly divided into three groups: focal seizures, generalized seizures, and other types that do not fit neatly into either category.Focal SeizuresFocal seizures begin in a single brain region. When awareness is preserved, they are called focal aware seizures and may cause sensations such as tingling, unusual smells, or flashing lights. When awareness is impaired, they are...
Epilepsy ll: Types01:22

Epilepsy ll: Types

Recurrent seizures, stemming from abnormal electrical activity in the brain, are the defining characteristic of epilepsy, a chronic neurological condition. Because seizure features vary greatly, epilepsy is classified using two systems: by seizure type and by epilepsy syndromes. These classifications enable clinicians to describe seizure patterns and select suitable treatment strategies.I. Classification by Seizure Type1. Focal EpilepsyFocal epilepsy begins in one hemisphere of the brain.

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Related Experiment Video

Updated: Jul 19, 2026

Methods for ECG Evaluation of Indicators of Cardiac Risk, and Susceptibility to Aconitine-induced Arrhythmias in Rats Following Status Epilepticus
08:28

Methods for ECG Evaluation of Indicators of Cardiac Risk, and Susceptibility to Aconitine-induced Arrhythmias in Rats Following Status Epilepticus

Published on: April 5, 2011

Psychogenic status epilepticus in children.

A Papavasiliou1, N Vassilaki, E Paraskevoulakos

  • 1Department of Neurology, Pendeli Children's Hospital, 8 Hippocrates Street, 152 36 Palaia Pendeli, Athens, Greece. theon@otenet.gr

Epilepsy & Behavior : E&B
|July 17, 2004
PubMed
Summary

Psychogenic status epilepticus (PSE) in children with epilepsy often presents diagnostic challenges. Prompt psychiatric intervention improved outcomes and reduced seizure recurrence.

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Interictal High Frequency Oscillations Detected with Simultaneous Magnetoencephalography and Electroencephalography as Biomarker of Pediatric Epilepsy
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Electromagnetic Source Imaging in Presurgical Evaluation of Children with Drug-Resistant Epilepsy
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Methods for ECG Evaluation of Indicators of Cardiac Risk, and Susceptibility to Aconitine-induced Arrhythmias in Rats Following Status Epilepticus
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Methods for ECG Evaluation of Indicators of Cardiac Risk, and Susceptibility to Aconitine-induced Arrhythmias in Rats Following Status Epilepticus

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Interictal High Frequency Oscillations Detected with Simultaneous Magnetoencephalography and Electroencephalography as Biomarker of Pediatric Epilepsy
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Area of Science:

  • Pediatric Neurology
  • Child Psychiatry
  • Epileptology

Background:

  • Psychogenic status epilepticus (PSE) involves prolonged seizures mimicking epilepsy but without epileptogenic activity.
  • Children with epilepsy may experience PSE, often alongside other neurological deficits and psychiatric comorbidities.

Purpose of the Study:

  • To describe epilepsy features, psychiatric profiles, psychosocial factors, and outcomes in children with PSE.
  • To highlight the importance of prompt diagnosis and psychiatric intervention for PSE in pediatric epilepsy patients.

Main Methods:

  • Case series of six children (aged 5-15) with confirmed PSE via video/EEG.
  • Inclusion of psychiatric assessments, psychosocial evaluations, and long-term outcome monitoring (average 3.6 years).
  • Utilized provocation and placebo techniques in two cases.

Main Results:

  • All patients had a history of epilepsy and received anticonvulsants prior to PSE suspicion.
  • Common comorbidities included depression, anxiety, OCD, and PTSD, often linked to psychosocial stressors.
  • Four patients showed improved psychiatric comorbidity and epilepsy control following psychiatric intervention; PSE did not recur in any patient.

Conclusions:

  • PSE is a significant consideration in children with epilepsy, with diagnosis often delayed in acute settings.
  • Management of comorbid psychiatric disorders is crucial for improving outcomes and reducing PSE recurrence.
  • Epilepsy severity and neurological deficits influence overall patient prognosis.