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Polypoidal choroidal vasculopathy in elderly Chinese patients
Feng Wen1, Changzheng Chen, Dezheng Wu
1Zhongshan Ophthalmic Center, Sun Yat-Sen University, 54 Xianlie Road, 510060 Guangzhou, PR China. wfwzt@163.net
Summary
Polypoidal choroidal vasculopathy (PCV) is common in elderly Chinese patients, frequently affecting men unilaterally. Lesions are typically found in the macular region and temporal vascular arcade.
Area of Science:
- Ophthalmology
- Medical Research
Background:
- Age-related macular degeneration (AMD) is a leading cause of vision loss in the elderly.
- Polypoidal choroidal vasculopathy (PCV) is an atypical form of exudative AMD.
- Understanding PCV prevalence and characteristics is crucial for diagnosis and treatment.
Purpose of the Study:
- To determine the frequency of PCV in elderly Chinese patients.
- To describe the clinical features and lesion characteristics of PCV.
- To investigate the demographic and topographic distribution of PCV.
Main Methods:
- Retrospective analysis of 166 patients aged 50+ with suspected exudative AMD.
- Utilized color fundus photography, fluorescein angiography, and indocyanine green (ICG) angiography.
- Identified PCV based on specific angiographic findings.
Main Results:
- PCV was diagnosed in 37 patients (22.3%) initially suspected of exudative AMD.
- PCV predominantly affected men (73.0%) and was unilateral in most cases (86.5%).
- Lesions were most commonly located in the macular region (61.9%) and temporal vascular arcade (21.4%).
Conclusions:
- Polypoidal choroidal vasculopathy is a significant condition in elderly Chinese populations.
- PCV exhibits a predilection for males and unilateral presentation.
- Macular and temporal vascular arcade locations are characteristic of PCV lesions.