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Magnetic resonance imaging abnormalities with septic encephalopathy.

P F Finelli1, D F Uphoff

  • 1Departments of Neurology and Pathology, Hartford Hospital, University of Connecticut School of Medicine, Hartford 06102-5037, USA. Pfinell@harthosp.org

Journal of Neurology, Neurosurgery, and Psychiatry
|July 20, 2004
PubMed
Summary

Septic encephalopathy can cause widespread brain abnormalities, even in transplant patients. Postmortem imaging revealed characteristic changes in the basal ganglia, thalamus, cerebellum, brainstem, and cerebrum.

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Area of Science:

  • Neurology
  • Nephrology
  • Radiology

Background:

  • Septic encephalopathy is a serious complication of infection.
  • Renal transplant recipients may have unique presentations of neurological disorders.

Observation:

  • A 48-year-old female renal transplant recipient presented with fever, seizures, and coma.
  • Neuroimaging demonstrated extensive abnormalities throughout the brain.

Findings:

  • Postmortem examination confirmed septic encephalopathy as the cause of death.
  • Magnetic resonance imaging (MRI) revealed bilateral abnormalities in the basal ganglia, thalamus, cerebellum, brainstem, and cerebral hemispheres.

Implications:

  • This case highlights the diverse neuroimaging findings in septic encephalopathy.

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  • Understanding these patterns is crucial for diagnosing and managing neurological complications in immunocompromised patients.