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Updated: Aug 10, 2026

Fixed Volume or Fixed Pressure: A Murine Model of Hemorrhagic Shock
Published on: June 6, 2011
Blood rheological abnormalities in the microcirculation during experimental traumatic shock
J Tatarishvili1, N Momtselidze, G McHedlishvili
1Microcirculation Research Center, I.Beritashvili Institute of Physiology, Tbilisi, Georgia
Objective:
To find whether the principal indices of blood rheological disorders related to the microcirculation undergo drastic changes during the traumatic shock.
Methods:
RBC aggregability and deformability, as well as the systemic hematocrit, were assessed in white laboratory rats with the techniques that provided us with direct and quantitative data.
Results:
We found that in the experimental animals the RBC aggregability was sharply increased, the RBC deformability significantly decreased, while the systemic hematocrit underwent considerable lowering during the traumatic shock.
Conclusion:
The blood rheological properties are significantly disordered during development of the traumatic shock.
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